KPC-Like Carbapenemase-Producing Enterobacteriaceae Colonizing Patients in Europe and Israel.

نویسندگان

  • A Baraniak
  • R Izdebski
  • J Fiett
  • M Herda
  • L P G Derde
  • M J M Bonten
  • A Adler
  • Y Carmeli
  • H Goossens
  • W Hryniewicz
  • C Brun-Buisson
  • M Gniadkowski
چکیده

In a 2008-2011 survey, 17,945 patients in 18 hospital units in Europe and Israel were screened for carriage of Klebsiella pneumoniae carbapenemase (KPC)-producing Enterobacteriaceae, resulting in identification of 124 positive patients. The isolates were dominated by Klebsiella pneumoniae sequence type 258 (ST258) KPC-2 and ST512 KPC-3, mainly from Greece and Italy, respectively, whereas Israeli isolates were of diverse species, clones, and KPC variants. Various blaKPC platforms were observed, among which IncFIIK-FIBK plasmids with blaKPC-2/-3 genes in the Tn4401a transposon prevailed.

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عنوان ژورنال:
  • Antimicrobial agents and chemotherapy

دوره 60 3  شماره 

صفحات  -

تاریخ انتشار 2015